Baisfu high quality Entecavir Cas No.: 142217-69-4 white crystalline powder for Antiviral treatment for chronic hepatitis

Short Description:

Entecavir's main application is in the antiviral treatment of chronic hepatitis B, and it is one of the first-line preferred drugs in clinical practice.

Product Detail

Baisfu high quality Entecavir Cas No.: 142217-69-4 white crystalline powder for Antiviral treatment for chronic hepatitis

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product attribute

Product Name: Entecavir

Cas No.: 142217-69-4

Appearance: White crystalline powder

Molecular weight: 277.279

Chemical name: 2 - Amino - 9-((1S,3R,4S)-4 - hydroxyl - 3-(hydroxymethyl)-2 - methylene-cyclopentyl) - 3H - purine - 6 - ketone

Appearance: White to off-white or yellow crystalline powder

Density: 1.81 g/cm³

Melting point: 249 - 252℃

Boiling point: 734.2℃ (760 mmHg)

Flash point: 397.9℃

Refractive index: 1.837

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Detailed Description

Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. Entecavir is a nucleoside analog (more specifically, a guanosineanalogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. The drug's manufacturer claims that entecavir is more efficacious than previous agents used to treat hepatitis B (lamivudine and adefovir). It also helps prevent the hepatitis B virus from multiplying and infecting new liver cells. Entecavir is also indicated for the treatment of chronic hepatitis B in adults with HIV/AIDS infection.

Functions

This product is a nucleoside analogue of guanine, which has inhibitory effect on hepatitis B virus (HBV) polymerase. It can be converted into active three phosphate by phosphorylation, and the half-life of three phosphate in cells is 15 hours. The natural substrate and HBV polymerase three phosphate deoxyguanosine competition, entecavir three phosphate can inhibit the viral polymerase (reverse transcriptase) of all three activities: (1) HBV polymerase promoter; (2) before the formation of genomic mRNA reverse transcription negative strand synthesis; (3) HBV DNA is the chain. The inhibitory constant (Ki) of entecavir three phosphate against HBV DNA polymerase was 0.0012 mu M. Entecavir three phosphate inhibited the alpha, beta, Delta DNA polymerase, and mitochondrial gamma DNA polymerase of cells less, and the Ki value was 18, as far as 160 M.


Baisfu high quality Entecavir Cas No.: 142217-69-4 white crystalline powder for Antiviral treatment for chronic hepatitis

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Company Profile

Xi’an Taima Biological Co., Ltd. was founded in 2008, is a technological export-oriented private enterprise with the Rights of Self-Managed Import and Export, specializing in active ingredients modernized and industrialization research, development, production, and sales of natural medical botany.
Our factory covers an area of 6,000 square meters equipped with advanced equipment and the production process is in accordance with FDA.
Since its inception, the company is aiming at providing every customer with top best quality products and superior service at a reasonable and competitive price, all the time. And in the past 9 years, we’ve gained great progress.
Our products are exported to countries all over the world: USA, countries in North America, South America, European countries like UK, Germany, Sweden, Greece, Finland, Norway, France, Italy, Russia, Ukraine, Estonia, Spain, Latvia, etc. Asia countries like Malaysia, Indonesia, South Korea, Thailand, Philippines, Vietnam, Singapore, etc. Our products are selling very well in these areas. And other countries like Australia, Mexico, Salvatore, Costa Rica, and so on. What’s more, for the high quality products and superior service we provide, we’ve been highly appreciated by our customers. We are getting more and more returning customer day by day.

Our advantage

1. Timely and efficient service to ensure communication with customers

2. Produce the products with different specs and sizes as your requirements.

3. SGS approved quality processes and standards. Advanced plant equipment ensures stable and high-quality goods.

4. Competitive price and high quality.

5. Sample is available.

6. OEM/ODM Service is available for private label and packaging and help you gain competitive advantage in the industry.

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Baisfu high quality Entecavir Cas No.: 142217-69-4 white crystalline powder for Antiviral treatment for chronic hepatitis

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Packing & Delivery

Package:1.1-10kg/bag, double plastic bags inside, aluminum foil Bag outside.
2.25kg/drum, double plastic bags inside.
3. According to your requirements.
Storage : Stored in a cool and dry well closed container and in ventilated area kept away from moisture and strong light or high temperature.
Delivery Time: within 3 -7 days after receiving payments.
Shipping Details: DHL, TNT, FEDEX or EMS.
Payment Terms: T/T, West Union, Paypal ,Alibaba Trade Assurance and Escrow service.

By Express: Suitable for under 50kg; Fast 3-7 Days; Door to door service;

By Air: Suitable for more than 50kg; Fast 3-7 Days; Professional broker needed;

By Sea: Suitable for more than 500kg; Slow 3-45 Days; Port to port ; Professional broker needed;

               FAQ             

Q1:Do You Accept Sample Orders?
Yes,we accept sample orders.
Q2 : What's Your MOQ?
We have no fixed requests on MOQ,it should according to Customers'actual demand.
Q3 : How To Assure The Quality Once Order Confirmed?
We have strict QC/QA management system,and Strict release procedures.
We prefer to deliver pre-shipment samples by Express Courier before shipment,or you can advise us your quality standard.
Q4 : Can We Have a Preview About The Product Quality before Our Order Despatching?
Sure,we always provide the relative Batach(s)'COA(s) before shipment.
Q5 : How Will You Deliver The Goods?
We have closed cooperation with most famous Shipping companies,Airlines,Express Couriers.
We'll suggest the best way according to your order quantity.

Q6 : What is Your Payment Terms?
We have flexible payment terms.
Q7 : What Is The Leading Time?
The leading time is different based on different quantity,we usually arrange shipment within 3-15 working
 days after order confirmation.

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